- Sinclair, E.W. (Photographer), Cooley, Sam. A (Photographer)1
- Sinkler, W.H.1
- Smith, A.C.1
- Smith, E.P.1
- Smith, Eliza Carolina Middleton Huger, 1824-19191
- Smith, James Allen1
- Smith, Simmie1
- Smith, Whitefoord1
- Snowden, Yates1
- Society for the Preservation of Spirituals1
- Somers S. Smith1
- Souder, S.T.1
- South Carolina Legislature1
- South Carolina Railroad Company1
- South Carolina. General Assembly. Commons House.1
- Southern Patriot, Charleston1
- Southern Prisoners' Relief Fun1
- St. John's Baptist Church Moderators and Clerks1
- Stanley, M.1
- State Teacher's College1