- Courtney Siceloff Collection of Gullah Folk Music and Spirituals, 19555
- Fairfield Plantation Papers5
- Frederick E. Kredel, M.D. Papers, 1925-19805
- Greenwood County Library Map Collection5
- Henry William Ravenel: Plants & Planter5
- James W. Colbert, Jr., MD, Oral History Project, 20095
- R.P. Hamer business letters, 18875
- Sidney and Lanny Palmer Collection5
- South Carolina Sheet Music Collection5
- South Caroliniana Library Oral History Collection5
- Upstate African American Genealogy5
- William Tennent III Journal and Album5
- Ale boycott records, 18904
- Bowman Family Papers, 1835-18924
- Charleston City Directories4
- Charleston Year Book, 19384
- Chesnut Family Papers, 1741-19004
- Claude Casey Collection4
- Confederate Spartanburg4
- Cote Bas and Mepkin Plantations Journals, 1865-18774