- Literary Annuals1
- Lucas-Porcher Family Papers, 1827-19721
- McBee Sons & Company Store Ledger Book, 1846-18611
- Minutes of the Annual Conferences of the Baptist, Episcopal, Lutheran, Methodist, and Presbyterian Churches in South Carolina, 1785-19204
- Mulberry Plantation Journals, 1853-1908 (bulk 1853-1889)1
- Proclamations, Politics, and Commerce: Broadsides from the Colonial Era to the Present at the South Caroliniana Library4
- Ron Swain Map Collection2
- Russell Maxey Photograph Collection1
- Slave Records in the Discrete Manuscript Collection1
- South Carolina Baptist Church Records86
- South Carolina Fall Line Collection3
- South Caroliniana Library Map Collection13
- South Caroliniana Pamphlet Collection1
- Spartanburg County Deed Books1
- St. Paul's Episcopal Church records, 1819-19711
- The American Revolution in South Carolina10
- The Joel Myerson Collection of Nineteenth-Century American Manuscripts, Images, and Ephemera1
- Vera Nathans Semel Papers, 1830-19851
- Waring Historical Library Artifact Collection1
- Waring Historical Library Inaugural Theses19