- Historic Southern Naturalists1
- John Shaw Billings Scrapbook1
- L.A. Hall Civil War and Reconstruction Eras Stereoscopic Images1
- Langdon Cheves III Hunting Notes & Art5
- Letters and Prints from the Campanella Collection of Giuseppe Garibaldi1
- Mary Motte Alston Pringle Receipt Book7
- Mayors of Columbia1
- Minutes of the Annual Conferences of the Baptist, Episcopal, Lutheran, Methodist, and Presbyterian Churches in South Carolina, 1785-19202
- Mulberry Plantation Journals, 1853-1908 (bulk 1853-1889)6
- Proclamations, Politics, and Commerce: Broadsides from the Colonial Era to the Present at the South Caroliniana Library2
- Records of the Church of the Holy Cross, 1788-19421
- Richard Furman and James C. Furman Collection1
- Ron Swain Map Collection1
- South Carolina Baptist Church Records90
- South Carolina and the Civil War5
- South Caroliniana Library Map Collection15
- St. Paul's Episcopal Church records, 1819-19711
- Stereographic Views of South Carolina2
- Thomas Benton Brooks Papers4
- Walter Pantovic Artifact Collection1