Collection
- Spartanburg County Deed Books33
- Spartanburg County In World War II1
- Spartanburg County in World War I Collection233
- Spartanburg County in World War II128
- Spartanburg Regional Healthcare System Collection203
- Spartanburg at the Dawn of the Twentieth Century2
- Sporting Journal of Maxcy Gregg2
- Springfield Plantation Journal,1831 - 18641
- St. Andrew's Society of Charleston Records, 1729-2001118
- St. Paul's Episcopal Church records, 1819-1971153
- Standard Federal (Columbia S.C.) Photograph Collection219
- State Library Photograph Collection 84
- Stereographic Views of South Carolina151
- Stereoscopic Photographs146
- Sterling High School Yearbooks1,461
- Stokes Grocery Store Ledger412
- Stoney Family Papers, 1775-19492
- Strom Thurmond Collection, Mss 1001,156
- Sullivan's Island Oral History Collection15
- Summerville Museum and Research Center Pamphlet Collection9