- Middleton Family Art Work, 1803-18671
- Middleton Family Papers, 1736-19291
- Millbrook account, n.d.1
- Mulberry Castle: Land of My Dreams1
- Natural Histories of Irvin Department of Rare Books1
- New insights in the American Civil Rights Movement: South Carolina Council on Human Relations records1
- No problems, only challenges : the autobiography of Theodore S. Stern1
- Pee Dee District Dental Society Records, 1933-19881
- Phillis Wheatley's Poems on Various Subjects1
- Pinckney-Means Family Papers, 1701-19831
- Polychronicon, Translated1
- Porcher Family History1
- Porcher Family Papers, 1740-1967 (bulk 19th century)1
- Private Collection1
- Program of... the Bishop's Council of the African Methodist Episcopal Church1
- Quiver1
- Report on the Census of Cuba, 18991
- Richard L. Johnson Medical Record Book, 1863-1864, 1867-18831
- Richmond Plantation Journal, 1859-18601
- Robert "Bob" Inglis Papers, Ephemera1