- Gussie Johnson Papers, 1940-200014
- UDC South Carolina Chapter13
- History of the University of South Carolina School of Medicine - Columbia12
- Midlands Memories12
- Bratton Family Papers, 1764-1983.11
- Isaiah DeQuincey Newman Papers11
- Philip Simmons Collection11
- South Carolina Historical Records Survey Collection11
- Historical and Governing Records, 1841-192510
- St. Mark United Methodist Church10
- B. A. Rodrigues Ottolengui Collection9
- Tri-Daily Meteorological Records, 18788
- Miriam DeCosta Seabrook and Herbert U. Seabrook Papers, 1882-19957
- Camp Sevier6
- Charleston Year Book, 19375
- Civic Services Committee Papers5
- The Joel Myerson Collection of Nineteenth-Century American Manuscripts, Images, and Ephemera5
- 1967 King Street Survey Collection4
- Charleston Year Book, 19384
- Cohen, Emanuel, Moses, Seixas Family Papers4