- Charles N. Bayless Photos of Charleston and Georgetown County, S.C.1,613
- Charleston Branch of the National Association for the Advancement of Colored People Papers, 1920-19953
- Charleston Earthquake 1886148
- Charleston Museum Earthquake Photographs203
- Charleston Museum Illustrated Newspapers Collection292
- Charleston Museum Plantation Photographs7
- Charleston Naval Shipyard Photographs819
- Charleston Souvenir Books2
- Charleston, S.C. Indelible Photographs1
- Charlotte Kaminski Scrapbook Collection1
- City of Charleston Board of Architectural Review Photographs Collection105
- Civil War and Reconstruction Era Stereoscope Photographs of the Port Royal Region106
- Clemson University Historical Images1,392
- Cleveland Family Collection 1
- Cleveland L. Sellers, Jr. Papers, 1934 - 200347
- Clubs, Organizations, and Sports42
- Cohen, Emanuel, Moses, Seixas Family Papers18
- Collected Civil War Papers of Colonel Benjamin Franklin Eshleman1
- College of Charleston Buildings and Grounds Photograph Collection1,059
- College of Charleston Scrapbooks and Photo Albums5