- Isaac Hayne Journal: Register, ca. 1764-17811
- Isabella Sarah Porcher Plantation Prescription Book1
- Isaiah DeQuincey Newman Papers1
- J. F. R. Papers, 1849-18551
- James N. Cochran Papers, 1838-18871
- John Henry McCray papers, 1929-198921
- John Ravenel Estate Book, 1862-18701
- Journal of Charles Cotesworth Pinckney's plantations, 1818-18191
- Journal of Robert Barnwell Plantations, 1838-18591
- Journal of Samuel Wilson, 18541
- Joyner Family Papers, 1842-18831
- Keziah Brevard Journal, 1860-18611
- Laura Benjamin Miller Collection on Judah P. Benjamin1
- Letter to Harriott Horry, ca. 17801
- Levi L. Kibler Letters Received1
- Lydia Jane Waring Estate Book, 1840-18471
- Manigault Family Papers, 1685-19711
- Materials towards a history of the Baptists in the provinces of Maryland, Virginia, North Carolina, South Carolina, Georgia1
- Mathurin Guerin Gibbs Plantation Register, 1824-18751
- Matthew J. & Arlyn Bruccoli Collection of F. Scott Fitzgerald1