- Sterling (Ill.)1
- Strode Tower15
- Stuckey (S.C.)6
- Sugar Hill Drive, Moncks Corner, South Carolina3
- Sullivans Island (S.C.)8
- Summerton (S.C.)14
- Summerville (S.C.)8
- Summerville, South Carolina3
- Summit (S.C.)7
- Sumter (S.C.)83
- Sumter County (S.C.)155
- Sumter Highway, Columbia, S.C.5
- Sumter Street, Columbia, S.C.98
- Sunset Boulevard, Columbia, S.C.2
- Sunset Drive, Columbia, S.C.3
- Surfside Beach (S.C.)9
- Swansea (S.C.)12
- Swansea, Lexington County, South Carolina, United States1
- Sycamore (S.C.)6
- Sylvan Drive, Columbia, S.C.1