- Clarendon County (S.C.)28
- Clemson (S.C.)15
- Clemson Avenue, Columbia, S.C.2
- Clinton (S.C.)2
- College Street, Columbia, S.C.4
- Colleton County (S.C.)4
- Colonial Life Boulevard, Columbia, S.C.1
- Columbia (S.C.)5,622
- Columbia Airport, West Columbia, S.C.4
- Columbia College Drive, Columbia, S.C.1
- Confederate Avenue, Columbia, S.C.1
- Conway (S.C.)5
- Country Club Drive, Columbia, S.C.5
- Covenant Road, Columbia, S.C.3
- Cypress Street, Columbia, S.C.2
- Darlington (S.C.)48
- Darlington County (S.C.)68
- Decker Boulevard, Columbia, S.C.9
- Devereaux Road, Columbia, S.C.1
- Devine Street, Columbia, S.C.23