- Scholarship, Education and Defense Fund for Racial Equality1
- School integration--South Carolina--Florence County1
- Schools1
- Schouboe, J. Edward1
- Scot, Emory1
- Scott, Hubert1
- Scranton (S.C.)--Maps1
- Seals, James W., d. 1973.1
- Seals, Rebecca--Pictorial works1
- Segregation in education--South Carolina--Clarendon County1
- Self, Ernest M.1
- Shivers, Jack--Correspondence.1
- Shoe Shop1
- Skelton, Neal1
- Skyscraper1
- Snow1
- Soda Jerk1
- Soil surveys--South Carolina--Florence County--Maps1
- Soils--South Carolina--Florence County--Maps1
- South Carolina Highway Patrol1