- Reedy River (S.C. : River)1
- Religion1
- Republic Pharmacy (Great Falls, S.C.)--Pictorial works1
- Revues1
- Roads--South Carolina--Map1
- Roses--Pictorial works1
- Sailing--Songs and music1
- Saint Matthews (S.C.)--Pictorial works1
- Santee River (S.C.)--Maps1
- Schenck, Joe, 1891-1930--Portraits1
- School yearbooks -- South Carolina -- Spartanburg County1
- Seeger, Alan, 1888-19161
- Seeger, Alan, 1888-1916--Correspondence1
- Sewerage1
- Shipping1
- Smiling--Songs and music1
- Smith, Bertie Mae1
- Smith, Eudora1
- Smith, Mendel L. (Mendel Lafayette), 1870-1934 -- Portraits.1
- Smoking--Songs and music1