- Roosevelt, Franklin D. (Franklin Delano), 1882-1945.1
- Ruins1
- Safaris1
- Sailing1
- Sailing craft1
- Saint Helena Sound (S.C.)--Maps, Topographic1
- Schmeling, Max, 1905-2005.1
- School children--United States.1
- School districts--South Carolina--Pickens County--Maps1
- School yearbooks -- South Carolina -- Spartanburg County1
- Scientific expeditions1
- Segregation1
- Smyrna (S.C.)--Maps1
- Soil surveys--South Carolina--Abbeville County--Maps1
- Soils--South Carolina--Abbeville County--Maps1
- South Carolina Penitentiary1
- South Carolina, Georgetown County, Andrews1
- Speeches, addresses, etc.1
- Sports publishing1
- St. Paul's Episcopal Church (Pendleton, S.C.)--Registers1