- Easterby, J. H. (James Harold), 1898-19603
- Eastern Air Lines4
- Eastland, James O. (James Oliver), 1904-19862
- Eastover (S.C.)10
- Eau Claire High School (Columbia, S.C.)5
- Edens, J. Drake (James Drake), 1925-2
- Edgar, Walter B., 1943-1
- Edwards, Ann Darlington, 1951-20141
- Edwards, James B., 1927-201420
- Eggs8
- Eisenhower, Dwight D. (Dwight David), 1890-19695
- Eisenhower, Mamie Doud, 1896-19792
- Eldorado automobile1
- Election workers3
- Elections36
- Elementary Schools2
- Elementary schools67
- Elephants25
- Elks (Fraternal order)2
- Elliott, Thomas Edward, 1929-1