- Railey, Clarence Butler1
- Rasor, John B., 1903-19861
- Rice, Ibzan Rex, 1884-19591
- Roller, Charles S., 1898-19011
- Sampey, John Richard, 1896-19671
- School superintendents1
- Schools, Medical--organization & administration--South Carolina1
- Scott, June David Marshall Bradbury, 1916-20051
- Sculptors1
- Shivers, Jack, 1915-19991
- Short, Jessie Mays Cox1
- Sims, Charles Furman, 1893-19611
- Sirrine, George William, 1847-19271
- Sirrine, Joseph Emory, 1872-19471
- Smith, Henry Holdman1
- Smith, Mallory Reynolds, 1918-19501
- Smith, Roy Jennings, 1913-19701
- Southern Baptist Theological Seminary1
- Southern, John Albert, 1904-19931
- Speer, James Harrel, 1895-19761